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Studies toward the Synthesis of Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc Trisaccharide

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Title Studies toward the Synthesis of Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc Trisaccharide
Author: Avery, Keri
Abstract: Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc trisaccharide has been shown to be a known sialic acid glycan linkage. The synthesis towards Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc trisaccharide involved using acetylation, deacetylation, benzylidenation, debenzylidenation, Koenigs-Knor glycosylation, Schmidt glycosylation, and sialylation reactions. The Galβ-(1-4)-GlcNAc disaccharide was successfully synthesized and will be employed in the studies towards the synthesis of Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc trisaccharide.
URI: http://hdl.handle.net/10192/99
Date: 2012-08-31

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